' AgeCare - Academy of Geriatric Cancer Research
Academy of Geriatric Cancer Research (AgeCare) is an Elite Research Center
located at Odense University Hospital in Odense, Denmark.

     
   
Minutes from the Danish Cancer Society Symposium 2016 organised by AgeCare

Click on left picture or here to download the minutes.


Click right picture or here to download the symposium program.
 
     
   
Former General Manager Line Haslund has (after excellent work for AgeCare) decided to stop in order to devote herself to the work of the Clinical Research Unit at the Department of Oncology at full time.
It is our pleasure to announce that Christina Nordenbæk has been appointed General Manager of AgeCare per November 1st 2016. Christina has been a full time Project Coordinator also at the Clinical Research Unit at the Department of Oncology.
     
   
We are proud to announce that the Academy of Geriatric Cancer Research in collaboration with the Danish Cancer Society will be hosting the symposium ” Cancer in the elderly”. The Symposium will take place from the 7-9 November 2016 in Copenhagen and the faculty will include national and international speakers. The symposium will uncover the topic “Cancer in the elderly” from basic research through translational research and also focus on implementation into clinical practice. Participation is free of charge, but only a maximum of 40 participants will be selected based on approval of an abstract. Applicants should submit an abstract summarizing one or more research projects in the area. The focus group is PhD students, Post Docs and senior scientist from the Danish research environment. Participants must apply the Danish Cancer Society.
For more information see www.cancer.dk/symposium
     
     
AgeCare was officially nominated an Elite Research Center at Odense University Hospital, December 2013, and work was initiated January 2014.

The 5-year research plan was evaluated by an Assessment Committee including eight international top scientist and will be reviewed on an annual basis by an international Advisory Board.

The research plan is divided into seven work packages focusing on cancer epidemiology, biomarkers, surgery, radiotherapy, medical cancer treatment and supportive care (e.g. comorbidity, polypharmacy and rehabilitation) in older cancer patients (AgeCare Project).

AgeCare consists of 70 researches from different cancer-related disciplines. A Steering Committee includes all work package leaders and the General Manager (AgeCare Team) and will convene twice a year and ad hoc. The Steering Committee will guide the overall strategy and national and international collaboration.

AgeCare will strive for cooperation with other groups and societies in the field e.g. the Cancer and Aging Research Group (CARG) and the International Society for Geriatric Oncology (SIOG) and there are several members from these groups among the 18 international members of AgeCare. (AgeCare Team).

AgeCare plans to initiate 17 PhD courses (3-year positions) and 10 post doc courses (3-year 50% positions) over the period of 2014 to 2018. Apart from the 17 PhD degrees, this should eventually result in 80-90 peer-reviewed publications in international journals in five years.

As of September 2015, 8 PhD courses and 2 post doc positions have been initiated (see initiated projects below). Publications from the first AgeCare related trials are listed on this web site (Publications).

AgeCare will receive funding from Odense University Hospital (14 mill DKK over the period of 2014 to 2018) and is committed to seek funding for the rest of the 50 mill DKK budget. So far the Danish Cancer Society, Velux Foundation, Odense University Hospital Research Council and the University of Southern Denmark have contributed.

Please contact one of us, if you are interested in cooperating with AgeCare.

     
Line Haslund RN  Jørn Herrstedt MD, DMSc   
     
General Manager  Head of AgeCare   
     
     
     
Ongoing AgeCare studies
     
PhD study: Importance of geriatric assessment in prediction of efficacy and tolerability of oncological therapy in older patients with gastrointestinal cancer.
Substudy: Randomised Nordic multicenter study – NORDIC 9
Substudy: Prediction of efficacy and toxicitiy of oncological therapy for older patients included in NORDIC 9.
Substudy: Older cancer patients’ attitude to chemotherapy.
AgeCare contact: Per Pfeiffer, Department of Oncology Odense University Hospital 
     
PhD study: Impact of CGA on QoL, overall survival and the need for admission in patients diagnosed with T1-2N0M0 NSCLC treated with SBRT – a single center randomized pilot study.
Substudy: A comparison of stereotactic body radiation therapy versus no treatment in medical inoperable patients with localized NSCLC T1-2N0M0
Substudy: A comparison of medical inoperable patients diagnosed with localized NSCLC treated with SBRT and patients with COPD without any cancer diagnosis
Substudy: A comparison of medical inoperable patients diagnosed with localized NSCLC treated with SBRT and patients with COPD without any cancer diagnosis
AgeCare contact: Olfred Hansen, Department of Oncology, Odense University Hospital.
     
PhD study: Significance of geriatric and biological assessment for optimal treatment of older cancer patients.
Substudy: Comorbidity among older gynecological cancer patients from the Region of Southern Denmark 2007-2011.
Substudy: Significance of oncologic treatment decision based on comprehensive geriatric assessment for optimal treatment of older gynecological and urological cancer patients.
Substudy: Biological assessment of older gynecological cancer patients with recurrent disease.
AgeCare contact: Jørn Herrstedt, Department of Oncology, Odense University Hospital
     
PhD study: Cardiotoxicity after radiotherapy for early breast cancer.
Substudy: Risk of pacemaker implantation subsequent to radiotherapy for early-stage breast cancer in Denmark 1982-2005.
Substudy: Risk of ischemic heart disease in women after radiotherapy for breast cancer .
Substudy: Incidence of heart disease in women treated with radiotherapy for breast cancer in Denmark 1977-2005.
Substudy: Risk of valvular heart disease in women after radiotherapy for breast cancer.
AgeCare contact: Marianne Ewertz, Department of Oncology, Odense University Hospital
     
PhD study: Treatment of breast cancer and risk of osteoporosis
Substudy: Treatment of breast cancer and risk of osteoporosis assessed by dual energy X-ray absorptiometry (DXA) and Xtreme-CT.
Substudy: Cross-sectional study assessing the risk of osteoporosis in patients with early-stage breast cancer, who received chemotherapy in 2009-2012.
AgeCare contact: Marianne Ewertz, Department of Oncology, Odense University Hospital
     
Study: Dose calculation based on cone beam CT images
AgeCare contact: Carsten Brink, Department of Oncology, Odense University Hospital
     
PhD study: Pre-natal hormonal influence on late life cancer
Substudy: Risk of sex-specific cancers in opposite-sex and same-sex twins in Denmark and Sweden.
AgeCare contact: Kaare Christensen, University of Southern Denmark
     
PhD study: The role of cancer in familial clustering of longevity
Substudy: Cancer and longevity - is there a tradeoff? A study of co-occurrence in Danish twin pairs born 1900-1918
Substudy: Low tobacco-related cancer incidence in offspring of long-lived siblings: a comparison with Danish national cancer registry data
Substudy: Cancer and aging: epidemiological and methodological challenges
Substudy: The health of spouses marrying into longevity-enriched families
Substudy: Cancer incidence in spouses to offspring from longevity-enriched families
AgeCare contact: Kaare Christensen, University of Southern Denmark
     
Study: Mortality of elderly patients with comorbidity and hematological malignancies
AgeCare contact: Henrik Frederiksen, Department of Hematology, Odense University Hospital
     
Study: Heritability of different cancer forms
AgeCare contact: Kaare Christensen, University of Southern Denmark
     
Study: Molecular analysis of cellular senescence
AgeCare contact: Morten Gjerstorff, University of Southern Denmark
     
Study: Circulating tumor miRNA and DNA in early detection and follow-up of early stage breast cancer
AgeCare contact: Henrik Ditzel, Odense University Hospital, University of Southern Denmark
     
Study: Molecular analysis of endocrine resistance in younger versus elderly postmenopausal breast cancer patients
AgeCare contact: Henrik Ditzel, Odense University Hospital, University of Southern Denmark
     
Study: Laparoscopic nephrectomy as outpatient in elderly patients
AgeCare contact: Lars Lund, Department of Urology, Odense University Hospital
     
Study: Outcome after laparoscopic nephrectomy versus hand assisted laparoscopic nephrectomy as outpatient
AgeCare contact: Lars Lund, Department of Urology, Odense University Hospital
     
Study: Liquid biopsy in elderly patients with small renal masses
AgeCare contact: Lars Lund, Department of Urology, Odense University Hospital
     
Study: Liquid biopsy in elderly patients with prostate cancer
AgeCare contact: Lars Lund, Department of Urology, Odense University Hospital
     
Study: Prediction of lung density changes after radiotherapy by cone beam computed tomography response markers and pre-treatment factors for non-small cell lung cancer patients
AgeCare contact: Carsten Brink, Department of Oncology, Odense University Hospital
     
Study: Automatic Planning of Head and Neck Treatment Plans
AgeCare contact: Carsten Brink, Department of Oncology, Odense University Hospital
     
Study: Stereotactic radiotherapy to patients with local non-small cell lung cancer - comorbidity, efficacy and toxicity of treatment
AgeCare contact: Olfred Hansen, Department of Oncology, Odense University Hospital.
     
Study: Dose Calculation based on Cone Beam CT images
AgeCare contact: Carsten Brink, Department of Oncology, Odense University Hospital
     
Study: Analysis of PET images acquired before treatment to validate a possible association between tumor texture and tumor control after radiotherapy of non-small cell lung cancer
AgeCare contact: Carsten Brink, Department of Oncology, Odense University Hospital
     
Study: Head and Neck Cancer and Esophageal cancer – weight loss, - prevention of tube feeding: Nutritional support, dietary counselling: New formulas of oral nutrition with higher lipid content
AgeCare contact: Jørgen Johansen, Department of Oncology, Odense University Hospital
     
Study: Head and Neck Cancer: Normal tissue function
AgeCare contact: Jørgen Johansen, Department of Oncology, Odense University Hospital
     
Study: Head and Neck Cancer: Elderly and fragile patients - alternative RT regimen
AgeCare contact: Jesper Eriksen, Department of Oncology, Odense University Hospital
     
Study: Exploration of the causes for registered improved survival of elderly multiple myeloma patients in Denmark (2009-2014 vs. 2005-2008)
AgeCare contact: Niels Abildgaard, Department of Hematology, Odense University Hospital
     
Study: Exploration of the survival of elderly patients with acute myeloid leukaemia treated with intensive chemotherapy and allogeneic bone marrow transplantation
AgeCare contact: Niels Abildgaard, Department of Hematology, Odense University Hospital
     
Study: DALIAH: Randomized Phase 3 trial: Danish study on low-dose interferon alpha vs. hydroxyurea in chronic myeloproliferative neoplasms. Analysis of efficacy, tolerability and Quality of Life in elderly patients treated with interferon alpha
AgeCare contact: Thomas Stauffer Larsen, Department of Hematology, Odense University Hospital
     
Study: NMSG 21/13: Randomised Phase 2 trial: Ixazomib-Thalidomide-low dose Dexamethasone induction followed by maintenance therapy with Ixazomib or placebo in elderly multiple myeloma patients.
AgeCare contact: Niels Abildgaard, Department of Hematology, Odense University Hospital
     
Study: Impact of cytogenetics and functional imaging findings on the treatment efficacy in elderly myeloma patients treated with non-intensive chemotherapy and novel agents (part of PhD project, Brian Østergaard, MD).
AgeCare contact: Niels Abildgaard, Department of Hematology, Odense University Hospital
     
Study: EMMY: Early initiated individualized training in newly diagnosed multiple myeloma patients; effects on physical function, physical activity, quality of life, pain, and bone disease. Analysis of impact in elderly patients (part of PhD project, Rikke Faebo Larsen, cand. Scient. San.)
AgeCare contact: Niels Abildgaard, Department of Hematology, Odense University Hospital
     
Study: Quality of Life in elderly Danish Multiple Myeloma patients; impact of new therapeutics (part of PhD project, Lene Kongsgaard Nielsen, MD)
AgeCare contact: Niels Abildgaard, Department of Hematology, Odense University Hospital
     
Study: Long term effects after multidisciplinary rehabilitation. A three year follow up study after RCT in prostate cancer patients
AgeCare contact: Karin Dieperink, Department of Oncology, Odense University Hospital
     
Study: ProCaRe - Prehabilitation and early Rehabilitation in Prostate Cancer Patients – a randomised study
AgeCare contact: Karin Dieperink, Department of Oncology and Danish Knowledge Centre for Rehabilitation and Palliative Care (REHPA), Odense University Hospital
     
Study: Family functioning and perceived supportive care from nurses during oncologic treatment in Denmark and Australia
AgeCare contact: Karin Dieperink, Department of Oncology, Odense University Hospital